Extended follow-up of cancer incidence in fluoride-exposed workers.
نویسندگان
چکیده
ed above, the letter below from one of our readers was submitted on June 10, 2004 to the Journal of the National Cancer Institute but was declined for publication. This journal [J Nat Cancer Inst] recently reported increased cancer incidence among cryolite industry workers.1 These findings merit comment on the implications for workers in other industries, particularly the aluminum industry. The study reported elevated bladder cancer rates among workers in the cryolite plant. Bladder cancer is also the main cancer reported in the aluminum industry.2 In the case of the aluminum industry, the increased cancer incidence is believed to be caused by exposure to Polycyclic Aromatic Hydrocarbons (PAH). However, in the cryolite plant, the workers were not exposed to PAH; “All cryolite plant processes were at room temperature, and there was no source of PAH other than some machinery and trucks entering and leaving the plant. We therefore concluded that there was no increased exposure to PAH among these workers.” [personal communication, Grandjean P; Oct 2, 2002]. The absence of PAH exposure among the cryolite workers suggests that airborne fluorides may be an important contributing factor to the increased incidence of bladder cancer in both the cryolite and aluminum industry. Unlike PAH, fluoride is present in both the cryolite and aluminum industries and is the major common exposure between the two
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ورودعنوان ژورنال:
- Journal of the National Cancer Institute
دوره 96 10 شماره
صفحات -
تاریخ انتشار 2004